Scale up from analytical to a preparative LC method with Thermo Scientific™ Hypersil™ PREP BDS C8 reversed phase preparative HPLC column. These columns come in a variety of dimensions including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. With similar selectivity to C18 columns and predictable elution order, C8 columns with base deactivation for reduced silanol activity are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations. Similar selectivity, less retention than C18 columns • Successful retention and separation of moderately hydrophobic analytes. • Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns. • Base deactivated silica. • C8 (USP L7) selectivity. • pH stable from 2 to 8. • Maximum temperature of 60°C. Faster separations • Higher analytical throughput compared to C18 alkyl chain chemistry. • Quicker compound elution due to reduced hydrophobic interactions. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Thermo Scientific™ preparative guard columns require the use of a preparative guard holder.
Maximize retention and loading using Thermo Scientific™ Hypersil™ PREP HS C18 reversed phase preparative HPLC Columns. These columns come in a variety of dimensions allowing you to easily scale up your analytical method, including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. These silica-based columns are packed with high surface area particles with a 100Å pore size offering C18 retention, an excellent choice for small molecule and drug purification applications. Excellent Choice for Routine Applications • C18 (USP L1) selectivity - high surface area particle with 100Å pore size. • pH stable from 2 to 9. • Maximum temperature of 60°C. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. These preparative guard columns require the use of a preparative guard holder.
Manufactured with a proprietary process and subjected to stringent quality control procedures, Thermo Scientific™ HyperREZ™ XP Carbohydrate Ca2+ LC Columns are used for the appropriate counter-ion to meet application requirements. Each column is individually tested to ensure column-to-column reproducibility. Polymer-based columns for carbohydrate analysis offer benefits to the chromatographer including temperature and pH stability, as well as enhanced solvent choices. • Designed for the determination of carbohydrates, saccharides, organic acids and alcohols • Efficient and reproducible monodisperse particles • Stable for long column lifetimes even at low pH and high temperatures
Available in H+, Ca+2, Pb+2, and Na+ forms, Thermo Scientific™ HyperREZ™ XP Carbohydrate Na+ LC Columns are the appropriate counter-ion to meet application requirements. Polymer-based columns for carbohydrate analysis offer benefits to the chromatographer including temperature and pH stability, as well as enhanced solvent choices. • Designed for the determination of carbohydrates, saccharides, organic acids and alcohols • Efficient and reproducible monodisperse particles • Stable for long column lifetimes even at low pH and high temperatures
Protect your analytical column from damage and contamination from nonvolatile materials using the ThermoScientific™ GuardGOLD™ Capillary columns.Facilitates Superior Analytic Performance Protects against column contamination caused by nonvolatile materials, extending the column lifetimeFocuses target analytes at the head of the analytical column, leading to better chromatographic peak shapeHighly deactivated to provide superior inertness, essential for analysis of active compoundsHigh maximum operating temperature of 360°C Ideal for High-Throughput, High-Resolution LC The UltiMate 3000 Rapid Separation Well Plate Autosampler is strongly recommended for high-pressure, high-resolution applications. Short injection cycle times make it ideal for high-throughput applications. It is available in both nonthermostatted (WPS-3000RS) and thermostatted (WPS-3000TRS) versions. Performance and Features • Injection volume precision typically <0.15% RSD for 5μL injections • High-precision drive mechanism to deliver superior injection linearity of r2 >0.9999 (5–90μL) • Wide injection volume range from 0.2 to 500μL using three syringe and loop combinations for maximum injection flexibility • Low gradient delay volume of 140μL (default) or 50μL (with 25μL sample loop) • Volumetric accuracy better than ±0.5% for 20μL injections allow easy method transfer from HPLC to UHPLC • Sample thermostatting to protect thermally-sensitive analytes (WPS-3000TRS)
Get maximum loading for your scale up from analytical to a prep LC method with Thermo Scientific™ Hypersil™ PREP HS C8 reversed phase preparative HPLC column. With similar selectivity to C18 columns and predictable elution order, C8 columns are ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations. By providing high surface area particles with a 100Å pore size, and a variety of dimensions including an option for XtendedLife hardware, which improves column lifetime by maintaining a uniform packed bed. Similar selectivity, less retention than C18 columns • Successful retention and separation of moderately hydrophobic analytes. • Ideal for fatty acids, which are too hydrophobic for analysis using C18 columns. • • C8 (USP L7) selectivity - high surface area particle with 100Å pore size. • pH stable from 2 to 8. • Maximum temperature of 60°C. Faster separations • Higher analytical throughput compared to C18 alkyl chain chemistry. • Quicker compound elution due to reduced hydrophobic interactions. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. These preparative guard columns require the use of a preparative guard holder.
Protect your analytical column from damage and contamination from nonvolatile materials using the ThermoScientific™ GuardGOLD™ Capillary columns.Facilitates Superior Analytic Performance Protects against column contamination caused by nonvolatile materials, extending the column lifetimeFocuses target analytes at the head of the analytical column, leading to better chromatographic peak shapeHighly deactivated to provide superior inertness, essential for analysis of active compoundsHigh maximum operating temperature of 360°C Ideal for High-Throughput, High-Resolution LC The UltiMate 3000 Rapid Separation Well Plate Autosampler is strongly recommended for high-pressure, high-resolution applications. Short injection cycle times make it ideal for high-throughput applications. It is available in both nonthermostatted (WPS-3000RS) and thermostatted (WPS-3000TRS) versions. Performance and Features • Injection volume precision typically <0.15% RSD for 5μL injections • High-precision drive mechanism to deliver superior injection linearity of r2 >0.9999 (5–90μL) • Wide injection volume range from 0.2 to 500μL using three syringe and loop combinations for maximum injection flexibility • Low gradient delay volume of 140μL (default) or 50μL (with 25μL sample loop) • Volumetric accuracy better than ±0.5% for 20μL injections allow easy method transfer from HPLC to UHPLC • Sample thermostatting to protect thermally-sensitive analytes (WPS-3000TRS)
Maintain exceptional peak shape and resolution for your scale up purification needs using Thermo Scientific™ Hypersil GOLD™ C18 preparative HPLC columns. Our columns come in a variety of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. These endcapped, ultrapure, silica-based columns deliver significant reduction in peak tailing using generic gradients with C18 selectivity. Hypersil GOLD columns give you confidence when scaling up from your analytical method. Novel Bonding • Proprietary functionalization and end-capping. • C18 (USP L1) selectivity. pH Stability • Robust performance at high pH. • Excellent column stability at low pH. Superior Performance • Highly symmetrical peak shapes. • Improved speed of analysis, efficiency, and sensitivity. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder. Customer Specific Orders • If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements. • Please contact your local sales representative for Customer Specific Orders. • Custom built columns are not eligible for returns.
Scale up your analytical method using Thermo Scientific™ Hypersil™ PREP ODS C18 reversed phase preparative HPLC Columns. These columns come in a variety of dimensions including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. This C18 column is a general purpose column used in a broad range of applications, perfect for routine workflows. For Routine Applications • C18 (USP L1) selectivity. • pH stable from 2 to 8. • Maximum temperature of 60°C. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Thermo Scientific™ preparative guard columns require the use of a preparative guard holder.
Maintain the sensitivity you need for your purification needs using Thermo Scientific™ Hypersil GOLD™ C8 preparative LC Columns. Best for scale up from analytical to prep LC method and ideal for analytes with medium hydrophobicity or when a less hydrophobic phase is required to obtain optimum retention. The lower hydrophobicity allows compounds to elute more quickly, yielding faster separations. Benefit from similar selectivity to C18 columns with a predictable elution order. Our columns come in a variety of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. Similar selectivity, less retention than C18 columns • Successful retention and separation of moderately hydrophobic analytes. • Best for fatty acids, which are too hydrophobic for analysis using C18 columns. • C8 (USP L7) selectivity. Faster Separations • Higher analytical throughput compared to C18 alkyl chain chemistry. • Faster compound elution due to reduced hydrophobic interactions. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.
Preperative Hypersil GOLD aQ polar endcapped C18 columns are stable in 100% aqueous mobile phase and provide enhanced retention and resolution of polar analytes. The HPLC columns come in a wide range of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. Alternative selectivity with polar endcapped C18 stationary phase • Polar functional group in endcap provides further interaction mechanism for separation of polar compounds. • Yields superior retention of polar compounds. • C18 (USP L1) selectivity. Stability in highly aqueous mobile phases • Applicable in 100% aqueous mobile phases. • No loss of performance or stability. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.
Easily scale up your analytical method and achieve maximum retention and loading using Thermo Scientific™ Hypersil™ PREP HS Si preparative HPLC columns. Packed with a bare silica, the high surface area particles with a 100Å pore size are made for normal phase chromatography of nonpolar and moderately polar organic compounds. These preparative HPLC columns come in a variety of dimensions including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. Normal phase chromatography • Silica to separate nonpolar and moderately polar organic compounds. • USP L3 - high surface area particle with 100Å pore size. • pH stable from 2 to .7 • Maximum temperature of 60°C. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. These preparative guard columns require the use of a preparative guard holder.
Separate water-soluble polymers and oligomers with Thermo Scientific™ Acclaim™ SEC-1000 Size Exclusion HPLC Columns. These resin-based, high-performance, size-exclusion chromatography columns cover molecular weight range: 7μm, 1000Å. The combination of a proprietary mono-dispersed multi-pore hydrophilic resin and small particle size provides high-resolution and good linearity of the calibration curve with no inflection points for accurate, reliable analysis of a variety of water-soluble polymers. The Acclaim SEC-1000 LC column is calibrated from 1,000 to 1,000,000 Daltons and can characterize high molecular weight polymers. High-Performance Analysis of Water-Soluble Polymers High-resolution analysis at reduced solvent consumption in available 4.6 x 300mm dimension Stable surface bonding leads to low column bleed and enhances compatibility with UV, RI, MS, ELSD and Thermo Scientific Dionex™ Corona™ Charged Aerosol Detectors
Separate water-soluble polymers and oligomers with Thermo Scientific™ Acclaim™ SEC-300 Size Exclusion Chromatography HPLC Columns. These resin-based, high-performance, size-exclusion chromatography columns cover molecular weight range: 5μm, 300Å. The combination of a proprietary mono-dispersed multi-pore hydrophilic resin and small particle size provides high-resolution and good linearity of the calibration curve with no inflection points for accurate, reliable analysis of a variety of water-soluble polymers. The Acclaim SEC-300 column is calibrated from 100 to 50,000 Daltons and offers good resolution for lower molecular weight polymers or oligomers. High-Performance Analysis of Water-Soluble Polymers • High-resolution analysis at reduced solvent consumption in available 4.6 x 300mm dimension • Stable surface bonding leads to low column bleed and enhances compatibility with UV, RI, MS, ELSD and Thermo Scientific Dionex™ Corona™ Charged Aerosol Detectors
HYPERSIL GOLD PFP 5UM MM PREP GUARD
Attain faster separations for hydrophobic analytes when you scale up using Thermo Scientific™ Hypersil GOLD™ C4 reversed phase preparative HPLC Columns, for your purification needs. These C4 columns provide excellent sensitivity and high efficiency, highlighting a lower hydrophobicity than C8 or C18 columns. These columns come in a variety of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. Similar selectivity, less retention than C18 or C8 columns • Outstanding retention and separation of very hydrophobic analytes with this short alkyl chain length, low hydrophobicity column. • Best for analysis of hydrophobic polypeptides and proteins. • C4 (USP L26) selectivity. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d.
HYPERSIL GOLD CN 5UM 10X8 MM PREP GUARD
HYPERSIL GOLD PEI HILIC 5UM 10X8 MM PREP GUARD
Easily scale up your analytical method using Thermo Scientific™ Hypersil™ PREP BDS Si preparative HPLC columns which are packed with a base deactivated silica for normal phase chromatography of nonpolar and moderately polar organic compounds.These preparative HPLC columns come in a variety of dimensions including an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed. Normal phase chromatography • Base deactivated silica to separate nonpolar and moderately polar organic compounds. • USP L3. • pH stable from 2 to 7. • Maximum temperature of 60°C. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Thermo Scientific™ preparative guard columns require the use of a preparative guard holder.
Hypersil PREP HS phenyl chemistry with high loading capacity and fully scalable from analytical to prep, suitable for all USP-L11 applications. A high surface area particle with a 100Å pore size and a phenyl bonded phase gives the stationary phase moderate hydrophobicity, making it ideal for the separation of analyte mixtures with varying polarity and aromaticity perfect for small molecule and drug purification needs. Unique Selectivity • Enhanced selectivity for aromatic and moderately polar analytes. • Selectivity complementary to that provided by alkyl chain phases. • Moderate hydrophobicity compared to C18. • Phenyl (USP L11) selectivity - high surface area particle with 100Å pore size. • pH stable from 2 to 8. • Maximum temperature of 60°C. Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs. Standard Threaded and Standard Flange Hardware • Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use. • Standard threaded hardware for column i.d. < 40mm. • Standard flange hardware for column i.d. ≥ 40mm. • Standard hardware can be modified on request to be compatible with SFC. XtendedLife Hardware • Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly. • Compatible with SFC and is available in dimensions up to 50mm i.d. Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. These preparative guard columns require the use of a preparative guard holder.
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